Uji Sitotoksisitas Ekstrak Ethanol 70 % Herba Ceplukan (Physalis angulata Linn.) Terhadap Sel WiDr Secara In Vitro

The Ethanol Extract of Physalis angulata Linn Inhibits COX-2 Activity in MCF-7 Cell In Vitro

Some studies showed that ceplukan (Physalis angulata Linn) have cytotoxic effects toward HeLa (cervical cancer), KB (Nasopharyngeal), Colo 205 (colon), Calu (Lung) and MCF-7 cells in vitro. This plant has cytotoxic effects toward rat P388 lymphocytic leukemia in vivo. One of the mechanisms of cytotoxicity is the inhibition of Cyclooxygenase-2 (COX-2) pathway. The purpose of this study was to de...

In Vitro Determination of Antioxidant Activity of Physalis Angulata Lnn

The present investigation was carried out to determine the antioxidant properties in methanolic extract of leaves, stem, fruit and roots of Physalis angulata (L). The antioxidant assay was carried out using free radicals DPPH, superoxide, nitric oxide, hydrogen peroxide and hydroxyl radical. Among the extracts tested fruit and leaf extracts were found to be significant in their antioxidant prop...

Physalis Angulata L . : an Ethanopharmacological Review

Genotoxic effect of Physalis angulata L. (Solanaceae) extract on human lymphocytes treated in vitro.

Physalis angulata L (Solanaceae) is a medicinal plant from North of Brazil, whose different extracts and infusions are commonly used in the popular medicine for the treatment of malaria, asthma, hepatitis, dermatitis and rheumatism. However, the genotoxic effects of P. angulata on human cells is not well known. The main purpose of the present study was to evaluate the in vitro genotoxic effects...

In vitro biological action of aqueous extract from roots of Physalis angulata against Leishmania (Leishmania) amazonensis

BACKGROUND Leishmaniasis is an infectious disease caused by various species of the protozoan parasites of the Leishmania genus and transmitted by phlebotomine sandflies. The protozoa multiply in phagocytic cells, mainly macrophages, which play an important role defending the organism from pathogens. The most effective treatment for leishmaniasis is the chemotherapy and besides the high cost, th...